Analysis of gastrointestinal acid-neutralizing potency of some commercial antacid tablet formulations

In dyspepsia, formulations known as antacids are regularly used to alleviate symptoms quickly possible. Gastric contents acidic; therefore, usually weak bases with the potential neutralize excess acid and raise gastric pH accordingly. Acid-neutralizing capacity is what determines effectiveness of an antacid. Some antacid tablets formulation from different manufacturers were tested for their acid-neutralizing patients in this study. The South-East region Nigeria had pharmacies vending brands. To remove bias study, brands coded A-F. Labels on all samples indicated that they would expire more than one year now. determine each tablet's capacity, titrimetric method was used. terms D, A, B, C, F, E showed greatest (8.2mEq/g), brand lowest (5.7 mEq/g). An analysis ANC found exceeded FDA standard >5mEq antacids. inexpensive, simple, easy-to-use could be routinely monitor tablet quality.